208P Lung cancer: Precise prediction

5-survival (5YS) and life span after radical surgery for non-small cell lung cancer (LC) patients (LCP) (T1–4N0–2M0) was analyzed. We analyzed data of 771 consecutive LCP (age = 57.6 ± 8.3 years) radically operated monitored in 1985–2022 (m 662, f 109; lobectomies 516, pneumonectomies 255; combined procedures 194; only surgery-S 620, adjuvant chemoimmunoradiotherapy-AT 151: CAV/gemcitabine+cisplatin+thymalin/taktivin+radiotherapy 45–50 Gy;T1=322, T2=255, T3=133, T4=61;N0=518, N1=131, N2=122, M0 771; squamous 418, adenocarcinoma 303, large 50; early LC 215, invasive 556. Variables selected study were input levels 45 blood parameters, sex, age, TNMG, type, tumor size. Regression, clustering, SEPATH, Monte Carlo, bootstrap, neural networks used to determine significant dependence. Overall (LS) 2240.9 1748.8 days 5-year survival reached 73%, 10 years – 64.2%, 20 43%. 503 lived more than 5 (LS 3126.6 1536 days), 145 5068.5 1513.2 days).199 died because 562.7 374.5 days). 5YS significantly superior comparison with (77.7% vs. 63.4%, P 0.00001). AT improved (64.4% 34.8%) (P 0.00003 by log-rank test) N1–2. Cox modeling displayed that depended on: phase transition (PT) early-invasive LC, PT N0—N12, ratio factors (ratio between cells- CC cells subpopulations), G1-3, histology, glucose, AT, circuit, prothrombin index, heparin tolerance, recalcification time 0.000–0.035). Neural networks, bootstrap simulation revealed relationships (rank 1), N0–N12 =2), thrombocytes/CC, eosinophils/CC, erythrocytes/CC, healthy cells/CC, segmented neutrophils/CC, lymphocytes, stick monocytes/CC; leucocytes/CC. Correct prediction 100% computing. cancer; N0–N12; factors; circuit; biochemical hemostasis system; AT; characteristics; type; dynamics; anthropometric data.